Laboratory medication – the underrated associate within the background – RHÖN-GESUNDHEITSBLOG


Greater than 60 p.c of the medical diagnoses made in Germany are based mostly on laboratory medication as practiced on the Institute for Laboratory Medication and Pathobiochemistry, Molecular Diagnostics on the College Hospital in Gießen and Marburg in Marburg.

"Loads is going on in our subject," says the director of the institute Professor Dr. Harald Renz. His institute is likely one of the largest diagnostic laboratory institutes in Germany. Amongst different issues, blood and urine are analyzed, 365 days a yr, 24 hours a day.

In an interview with the RHÖN well being weblog, the skilled talks in regards to the particular experience of his institute, which is especially in demand within the period of the corona pandemic, about the benefits of so-called customized medication, and about one in all his tasks that has not too long ago obtained worldwide consideration.

Professor Renz, you and your workforce have been represented within the worldwide media in latest weeks. The purpose was that you simply developed two merely constructed ventilators on the clinic in Marburg. What precisely was it about?

It is a actually nice initiative that was launched by our physicists. The main focus is on the query of whether or not it’s not potential to fabricate a quite simple ventilator utilizing very rudimentary supplies that may be purchased within the ironmongery store.

Though the marketplace for such gadgets isn’t essentially Germany, is it?

You would assist all of the individuals who want air flow, however at present haven’t any entry to the highest intensive care medication that we’ve got on this nation. And all these areas of the world the place there’s a dramatic scarcity of gadgets. Amongst different issues, I take a look at the USA, however quickly additionally at Africa.

You’re director of the Institute for Laboratory Medication and Pathobiochemistry, Molecular Diagnostics, that sounds primarily scientific to the layperson. What precisely do you do and what function does your institute play within the present Covid 19 disaster?

We look at all fluids within the human organism, primarily blood, but in addition urine, for instance. We are able to then establish potential malregulations within the human physique that contribute to the event, improvement or worsening of a illness.

In a approach, laboratory medication has a distinct segment existence in public notion regardless of its undisputed significance for medication. The principle motive for that is that it principally runs within the background.

And what’s the particular product of your institute?

Diagnostic assessments, that are additionally known as "laboratory assessments". They make a vital contribution so {that a} dependable prognosis can solely be made within the first place. Right here we work in shut cooperation with the colleagues in Pathology, who are usually not coping with liquids, however with tissue samples. Thirdly, there’s additionally imaging, which works with X-rays, ultrasound, computed tomography or nuclear medication, for instance. The time to categorise.

So your institute is in excessive demand within the clinics?

It really works 24 hours a day, seven days every week, 365 days a yr. Blood samples from sufferers can subsequently be given repeatedly, which we then look at instantly and instantly. Amongst different issues, this is essential for the emergency room, the place the colleagues must know in a really brief time whether or not their affected person has a coronary heart assault or a stroke, whether or not the kidney remains to be working or whether or not one other organ is inflicting issues. Generally it’s irritation that we will decide.

And in instances of Corona?

We are able to then decide whether or not a affected person remains to be in a position to soak up oxygen. If this isn’t the case, he should after all be ventilated instantly. As well as, it’s at present essential to first clearly acknowledge whether or not or not it’s a affected person with Covid-19. Due to course there are a lot of ailments which might be related to cough, sore throat, hoarseness, physique aches and fever.

What when you have been recognized with Covid-19?

Then it’s crucial to find out how badly the affected person is affected. Right here we’re primarily considering medical professionals whether or not there’s a so-called overreaction of the immune system.


As a result of that is typically decisive for whether or not a affected person must be positioned in an intensive care unit the place air flow could even be crucial. We additionally know that many corona sufferers additionally present issues in different organs. That is all in regards to the cardiovascular system. Generally it seems to be like a small coronary heart assault for medical professionals. Circulatory issues can even happen, which within the worst case set off a stroke. Final however not least, the operate of the liver and kidneys may also be impaired.

So it's about trying on the affected person as holistically as potential?

Particularly when we’ve got a corona affected person in the home, it is extremely essential to take take a look at his situation. Within the additional course, we naturally verify whether or not there’s an enchancment or a deterioration. The intention is that the intensive care physicians can react adequately based mostly on our laboratory medical evaluation.

What number of laboratory values ​​do you go on every year?

Over 10 million. Our portfolio consists of over 800 totally different laboratory assessments: blood photos, urine diagnostics, hormone and metabolism measurements, measurements of drug ranges and poisoning, allergy diagnostics, but in addition diagnostics of autoimmune ailments comparable to rheumatism.

How will you think about your workforce's on a regular basis life?

Round 4,000 to five,000 tubes of affected person samples arrive right here each day. Then it's our flip to look at these samples. After which we ship the outcomes again to the specialists from the clinics. We regularly get questions from them. That is virtually practiced laboratory medication, so to talk.

Would you want to try the way forward for your self-discipline?

An enormous matter that’s already very current is that of laboratory medication informatics. That is about linking analysis and affected person information, letting them “speak” to one another, so to talk, in order that the care of our sufferers turns into even higher.

"Precision medication" is a catchphrase …

Or "customized medication". This impacts laboratory medication particularly, as a result of sooner or later it is going to be much more essential to find out how every of our sufferers is coping with their underlying illness.

Let's take a affected person with a continual lung illness like bronchial asthma. In the present day it’s merely not sufficient to say that the affected person has this illness. As a substitute, we have to analyze precisely what sort of bronchial asthma he’s affected by. There may be, for instance, allergic or non-allergic bronchial asthma. As well as, there are a lot of extra differentiators. The duty of laboratory medication is to assign these high quality sides to such continual ailments.

Why is that essential?

As a result of in future every of those high quality sides shall be handled in another way. In fashionable medication, the motto is not “one therapy for all sufferers”, however quite to research every affected person with its particular options and to construct a tailored remedy idea for him. That is customized medication. And right here laboratory medication is an important constructing block.

Harald RenzYour skilled in laboratory medication:
Professor Dr. Harald Renz
Director of the Institute for Laboratory Medication and Pathobiochemistry, Molecular Diagnostics of the College Hospital Gießen & Marburg in Marburg