Risk-adapted PSA test: which risk factors does a man bring with him?
The G-BA will first wait for the results of the named study PROBASE exist. It is currently running in Germany and almost 47,000 men are taking part. The aim of the study is to develop a risk-adapted screening strategy for prostate cancer. This means that doctors do not determine the PSA value across the board as part of a series check-up for every man over a certain age.
Rather, a man’s individual risk profile for this type of cancer plays a role. Risk factors could include a family history of prostate cancer or an elevated PSA level at the age of 40 or 45. Urologist Frank Schiefelbein is certain: “We need a more differentiated approach to the PSA value. Therefore, a risk-adapted PSA test will have the greatest importance in the future. “
Prof. Arnulf Stenzl, the DGU President, explains: “The G‑BA fails to take into account that the determination of the PSA value is not about a systematic, purely age-related screening. ”Unfortunately, the term“ screening ”implies this. Rather, the PSA test is an essential cornerstone for risk-adapted, individualized early detection of prostate cancer. “This differentiated use of PSA determination minimizes false-positive findings as well as overdiagnoses and therapies to a level that is justifiable in oncology”, Stenzl continues. The G-BA I have thus wasted a “previously unique opportunity to improve prostate cancer early detection based on the state of the art.”